Nearly Four thousand years (4000) ago the early Sumerians made a surprising discovery. For the various kind of pain, they followed a strange thing. They scraped the bark of a special kind of tree. Some of them ate it. Some of them boiled that bark and drunk the water. Latterly little bit Their pain disappeared. However, they didn’t know what has happened or what they’d found. It was destined to affect the future course of medicine. historical story and benefits of aspirin medicine such an interesting thing. That surprising discovery was done by the Sumerians, was a forerunner to the valuable medicine known today as Aspirin. The active ingredient of Aspirin is found normally in willow trees. However, in other wild plants, It laid the foundation of the medical traditions of Sumer, Ancient, Egypt, ancient Greece, and other cultures.
The father of modern medicine who is the Hippocrates first recommended the two factors. The first thing is the Chewing willow bark caused for pain relief. And the other thing is willow leaf tea affect to relieve the pain of childbirth. In addition, there are a lot of benefits of aspirin.
Relationship between Willow bark and the salicin
However, it took over two thousand years for us to comprehensively investigate its potential. In the mid-eighteenth-century, a scientist named Edward stone carried five years of experiments using that willow bark. Willow bark Crushed into a powder and then it Eaten could cure a fever. It took nearly another seventy years for a German pharmacist Johann Buckner to finally identify and purify the substance that made all this possible a compound called salicin. Willow bark and other salicin rich plants like the herb meadowsweet were routinely used by doctors to ease pain fever and inflammation.
However, identifying the exact compound unexpectedly opened up the potential of manipulating Its form.
Acetylsalicylic acid and officially introduce Aspirin
In eighteen fifty-three a French chemist managed to chemically synthesized a compound creating a substance called acetylsalicylic acid. Then, in eighteen ninety-seven the Bayer pharmaceutical company Founded that a new method. And also introduced a new pain reliever called Aspirin also began marketing the compound. The first synthetic pharmaceutical drug was widely recognized is aspirin. Aspirin came Originally from bears brand name. A for acetyl and spur for meadowsweet who is botanical name is Spiraea Almeria. Soon, Aspirin became synonymous with Acetylsalicylic acid.
Benefits of aspirin
When we talk about the historical story and benefits of aspirin, Pain relief is a one of the major benefits of aspirin. And also, many Information related problems like rheumatoid arthritis and pericarditis.It causes inflames the fluid-filled sac around the heart and callous sake disease where blood vessels become inflamed.
However, notwithstanding aspirin’s clinical incentive now researchers despite everything didn’t have the foggiest idea of how it functioned. In the nineteen sixties and seventies Swedish and British scientists changed that. They demonstrated that the medication interferes with the creation of specific synthetics called the prostate gland.
Which controls the transmission of Pain sensations and Information?
Reduced the form of blood clots
But, in the nineteen-eighties, further discoveries about aspirin’s benefits revived interest in it. In fact, the nineteen eighty-two Nobel prize winners also demonstrated that aspirin slows the production of thromboxane. Thromboxane causes clumping of platelets, Which in turn Form blood clots.
Reduce the risk of heart attack
When we talk about the historical story and benefits of aspirin, aspirin use to reduced heart attack risk. A landmark clinical trial showed that aspirin reduced heart attack risk by forty-four percent in participants who took the drug. Today we prescribe it to people
At risk of heart attack or stroke. Because it cuts the likelihood of clots. And also, Forming in the arteries that supply the heart and brain.
Even more, intriguingly there’s a growing body of research that suggests aspirin reduces the risk of getting and dying from cancer. Especially colorectal cancer. The reason might be for this aspirin’s anti-platelets effects by reducing platelet activity. Aspirin may certain protein levels that can help cancer cells spread is decreased by the aspirin. These kinds of researches have caused aspirin transformed from no more than a pain reliever to potentially lifesaving treatment.
Overdose effects of aspirin
In nineteen eighty-two that discovery one of the researchers a Nobel prize in medicine. Over time research has also uncovered aspirin’s risks. Overdose of aspirin can cause bleeding in the brain and the intestines. As well as, can also trigger Reyes syndrome. It is a rare situation. but, oftentimes the fatal illness that has an effect on the brain and liver in children with an infection.
And in the late twentieth century introduced newer pain killers with fewer side effects like acetaminophen and Ibuprofen. Because of that, the success of the aspirin had been suppressed.
Today we consume about one hundred billion aspirin tablets each year. And also, researchers continue searching for new applications. Already Aspirin’s versatility has transformed modern medicine. Which is Astounding considering its unassuming beginnings in scratching of willow bark.